Computational investigations on the impact of cell architecture and its remodeling on cell physiology (MCB)
Cell shape and architecture are tied to cell function. A heart cell is shaped like a rod, an epithelial cell on the skin is shaped like a column or brick. My research group, Cell Structure and Mechanobiology Group, is interested in understanding how important cell shape and architecture is to a cell’s function. We are also interested in determining the impact that cell architecture remodeling has on a cell’s function. In this talk I will present our current investigations into the impact of changes to mitochondrial organisation heart cell contractility. I will also discuss what I think are some important questions about cell form and function that stem from what we have learned to date.
Dr Vijay Rajagopal, Department of Biomedical Engineering, University of Melbourne